A Non-canonical Function of BMAL1 Metabolically Limits Obesity-Promoted Triple-Negative Breast Cancer

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Clinicopathological Features of Non-metastatic Triple Negative Breast Cancer

Background: Triple negative breast cancer (TNBC) is reported to be associated with a high risk of recurrence, poor overall survival (OS), and disease-free survival (DFS) rates. This study evaluated the clincopathological features and survival of non-metastatic TNBC women in the capital of Iran compared with other areas of the world. Methods: In a retrospective study, 119 women with TNBC based ...

متن کامل

Association of HDAC8 Expression with Pathological Findings in Triple Negative and Non-Triple Negative Breast Cancer: Implications for Diagnosis

Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...

متن کامل

MRI Findings of Triple Negative Breast Cancer: A Comparison with Non-Triple Negative Breast Cancer

JKSMRM 14:95-102(2010) Department of Radiology, College of Medicine, The Catholic University of Korea Clinical Research Coordinating Center, College of Medicine, The Catholic Medical Center Department of Surgery, College of Medicine, The Catholic University of Korea Received; September 27, 2010, revised; November 17, 2010, accepted; December 1, 2010 Corresponding author : Sung Hun Kim, M.D., De...

متن کامل

clincopathological features of non-metastatic triple negative breast cancer

background: triple negative breast cancer (tnbc) is reported to be associated with a high risk of recurrence, poor overall survival (os), and disease-free survival (dfs) rates. this study evaluated the clincopathological features and survival of non-metastatic tnbc women in the capital of iran compared with other areas of the world. methods: in a retrospective study, 119 women with tnbc based o...

متن کامل

Future of Triple Negative Breast Cancer: Can Immunotherapy Treat This Deadly Subtype of Breast Cancer?

Triple negative breast cancer (TNBC): challenges and solutions via the immune cells TNBC is one of the most complicated types of breast cancer to treat. It is generally diagnosed based on the absence of three receptors: estrogen, progesterone, and human epidermal growth factor receptor 2 (HER2) and is thus defined as a triple negative. TNBC is often more aggressive with lower survival rates...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: iScience

سال: 2020

ISSN: 2589-0042

DOI: 10.1016/j.isci.2020.100839